Melittin-stimulated antimycobacterial activity of the membrane fraction isolated from phagocytes of guinea pigs.
نویسنده
چکیده
Virulent tubercle bacilli were incubated in Kirchner semi-solid agar medium with the membrane fraction prepared from guinea-pig peritoneal exudate cells. A marked inhibition of mycobacterial growth was observed in the presence of added melittin which is known as an activator of membrane phospholipase A. The bactericidal activity in a buffer environment was also demonstrated by the fraction alone and that stimulated by melittin.
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عنوان ژورنال:
- Japanese journal of medical science & biology
دوره 39 1 شماره
صفحات -
تاریخ انتشار 1986